- 英文名称
- Ingenol
- 分子式
- C20H28O5
- 分子量
- 348.43
- 中文别名
- 巨大戟萜醇; 巨大戟二萜醇; (1AR,2S,5R,5AR,6S,8AS,9R,10AR)-1A,2,5,5A,6,9,10,10A-八氢代-5,5A,6-三羟基-4-(羟甲基)-1,1,7,9-四甲基-1H-2,8A-甲醇环戊二烯并[A]环丙烷[E]环癸烯-11-酮; (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-三羟基-4-(羟甲基)-1,1,7,9-四甲基-1a,2,5,5a,6,9,10,10a-八氢-1H-2,8a-甲桥环戊并[a]环丙烷并[e][10]环烯-11-酮; ingenol; (1ar,2s,5r,5ar,6s,8as,9r,10ar)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1h-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one; 1alpha,2,5,5alpha,6,9,10,10alpha-Octahydro-5,5alpha,6-trihydroxy-4-hydroxymethyl-1,1,7,9,-retramethyl-1H-2,8alpha-m; 1A,2,5,5A,6,9,10,10A OCTAHYDRO-5,5A,6-TRIHYDROXY4(HYDROXYMETHYL)1,1,7,9-TETRAMETHYL1H-2,8 AMETHANOCYCLOPENTA[A]CYCLOPROPA[E]CYCLODECEN-11 ONE; (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-Trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one; (1S,4S,5R,6R,9S,10R,12R,14R)-4,5,6-Trihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyltetracyclo[7.5.1.0.0]pentadeca-2,7-dien-15-one; 1aa,2a,5b,5ab,6b,8ab,9a,10,10aa-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one
- 用途
- 巨大戟醇是来源于大戟科大戟属植物大戟全草、甘遂或千金子的萜类活性成分，具有显著抗癌、抗病毒活性，可作为合成巨大戟醇甲基丁烯酸酯（Picato）的关键中间体，用于日光性角化病（AK）的局部治疗；其含量可通过HPLC-ELSD法测定，作为甘遂饮片的质量控制方法。
