- 英文名称
- 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-D-uridine
- 分子式
- C31H30N2O7
- 分子量
- 542.58
- 中文别名
- 5'-DMTR-2,2'-脱水胸腺嘧啶; 5'-(O)-(4,4'-二甲氧基三苯甲基)-5-甲基-2,2'-脱水-β-D-阿拉伯糖呋喃糖基尿嘧啶; (2R,3R,3AS,9aR)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxy-7-methyl-3,3a-dihydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6(9aH)-one; 2,2'-Anhydro-5'-O-DMT-5-methyluridine; 5'-DMTr-2,2'-anhydrothymidine; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-7-methyl-, (2R,3R,3aS,9aR)-; 5’-O-(4,4’-Dimethoxytrityl)-5-methyl-2,2'-anhydro-β-D-arabinofuranosyl uracil; 2,2'-anhydro-1-[2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl-5-methyluridine]
- 用途
- 概述
5'-DMTr-2,2'-anhydrothymidine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。
