150780-67-9 5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基-N-异丁酰基鸟苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺

中文名称: 5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基-N-异丁酰基鸟苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺
英文名称: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS号
分子式: C₄₅H₅₆N₇O₉P
分子量: 869.94
更新日期: 2026-06-23

名称和标识

中文名: 5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基-N-异丁酰基鸟苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺
英文名: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS号: 150780-67-9
分子式: C45H56N7O9P
分子量: 869.94
中文别名: (2R,3R,4R,5R)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-5-(2-异丁酰胺基-6-氧代-1H-嘌呤-9(6H)-基)-4-甲氧基四氢呋喃-3-基 (2-氰基乙基)二异丙基亚磷酰胺; 2'-OME-IBU-RG 亚磷酰胺单体; DMT-2′-O-甲基-RG(IB)酰胺; 2'-OME-IBU-G -CE亚磷酰胺单体; 2'-OME-IBU-G 亚磷酰胺单体; N2-异丁酰基-5'-O-DMT-2'-甲氧基鸟苷-3'-氰乙氧基亚磷酰胺; 2'-OME-G(IBU)亚磷酰胺单体; 2'-OMe-ibu-G亚磷酰胺单体
英文别名: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 2'-OMe-G(ibu) Phosphoramidite; 2'-OMe-ibu-G Phosphoramidite; 2'-OMe-G(iBu)-3'-phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; DMT-2'O-Methyl-rG(ib) Phosphoramidite; DMT-2'-O-Me-rG(ib) amidite; N-{9-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-methoxyoxolan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-2-methylpropanamide; DMT-2'-O-Me-G(iBu)-CE Phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-O-methyl-N-(2-methylpropanoyl)guanosine; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2’-O-Methy-rG(N-ibu)Phosphoramidite; N-blocked-5'-O-DMT-2'-O-Me CED guanosine phosphoramidite; 5'-O-DMT-2'-O-Me-rG(N-iBu)-3'-CEDPA; 5'-O-DMT-2'-O-Me-G(ibu) phosporamidite; ibu-2'-OMe-G Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-methylguanosine; 2'-O-Methyl Guanosine (n-ibu) CED Phosphoramidite

物化属性

LogP: 9.93
PSA: 201.65 Å²
XLogP3-AA: 5.6
储存条件: 2-8°C，保存于惰性气体中
外观: 白色至淡黄色粉末，对热和湿敏感
溶解度: 可溶于乙腈（轻微）、氯仿（轻微）、甲醇（轻微，超声处理）
熔点: 138-140 °C

安全信息

安全说明

干冰运输。危险性质：非危险化学品。WGK Germany:3。存储类别:11 - 可燃固体

生产及用途

用途与制备

5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基-N-异丁酰基鸟苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺是一种修饰过的亚磷酰胺单体，可用于寡核苷酸的合成。

化学合成；生命科学

词条详情加载中…

150780-67-9 5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基-N-异丁酰基鸟苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺

中文名称

5'-O-(4,4-二甲氧基三苯甲基)-2'-O-甲基-N-异丁酰基鸟苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺

英文名称

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS号

分子式

C₄₅H₅₆N₇O₉P

分子量

869.94

更新日期

2026-06-23