- 英文名称
- Elastatinal
- 分子式
- C21H36N8O7
- 分子量
- 512.56
- 中文别名
- (((S)-2-(((S)-5-氨基-1,5-二氧代-1-(((S)-1-氧代丙烷-2-基)氨基)戊-2-基)氨基)-1-((S)-2-氨基-3,4,5,6-四氢嘧啶-4-基)-2-氧代乙基)氨基甲酰基)-L-亮氨酸; (2S)-2-[(4S)-2-氨基-1,4,5,6-四氢-4-嘧啶基]-N-[[[(1S)-1-羰基-3-甲基丁基]氨基]羰基]甘氨酰-N1-[(1S)-1-甲基-2-氧乙基-L-谷氨酸甲酰胺; ELASTASE抑制剂; (((S)-2-(((S)-5-Amino-1,5-dioxo-1-(((S)-1-oxopropan-2-yl)amino)pentan-2-yl)amino)-1-((S)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-oxoethyl)carbamoyl)-L-leucine; elastatinal from microbial source; Leu-co-cpd-Gln-Ala-h; N-[-N-ALPHA-CARBONYL-CPD-GLN-ALA-AL]-LEU; L-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]glycyl-N1-(1-methyl-2-oxoethyl)-L-glutamamide, stereoisomer; L-Glutamamide, (2S)-2-(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-N-(1S)-1-carboxy-3-methylbutylaminocarbonylglycyl-N1-(1S)-1-methyl-2-oxoethyl-; (2s)-2-[(4s)-2-amino-1,4,5,6-tetrahydro4-pyrimidinyl]-n-[[[(1s)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-n1-[(1s)-1-methyl-2-oxoethyl-l-glutamamide; Nα-[2-(2-Amino-1,4,5,6-tetrahydropyrimidin-4-yl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]-L-glycyl]-N1-(1-methyl-2-oxoethyl)-L-glutaminamide
- 用途
- 生命科学领域应用;作为有效和竞争性的弹性蛋白酶抑制剂，Ki为0.21μM，与白细胞弹性蛋白酶相比更有效抑制胰弹性蛋白酶，对人白细胞糜蛋白酶样蛋白酶无活性
