- 英文名称
- Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate
- 分子式
- C16H27N6O5PS
- 分子量
- 446.46
- 中文别名
- Sp-环状3',5'-氢硫代磷酸酯腺苷水合物; (S)-腺苷环 3',5'-(氢硫代磷酸酯)三乙胺盐; 化合物 SP-CAMPS TRIETHYLAMINE; (2S,4AR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-mercaptotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide compound with triethylamine (1:1); Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate; 6-(6-aminopurin-9-yl)-2-oxido-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol,triethylazanium; Sp-cAMPS triethylamine; SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE; adenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-camps),triethylammonium; SP-CYCLIC 3',5'-HYDROGEN PHOSPHOROTHIOATE ADENOSINE TRIETHYLAMINE; ADENOSINE 3',5'-CYCLIC PHOSPHOROTHIOATE-SP, TRIETHYLAMMONIUM SALT; ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, SP-ISOMER TRIETHYLAMMONIUM SALT; ADENOSINE-3',5'-CYCLIC MONOPHOSPHOTHIOATE, SP-ISOMER TRIETHYL AMMONIUM SALT; CAMPS-SP, TRIETHYLAMMONIUM SALT; CAMPS TEA, SP-ISOMER; SC-CAMPS TRIETHYLAMINE (SP-ADENOSINE-3', 5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLA
- 用途
- 作为cAMP类似物，是依赖cAMP的PKA I和PKA II的有效激活剂；是竞争性磷酸二酯酶(PDE3A)抑制剂，Ki为47.6 µM；以EC50为40 μM结合PDE10 GAF域
