- 英文名称
- Actein
- 分子式
- C37H56O11
- 分子量
- 676.83
- 中文别名
- 阿克特素; 升麻亭; (1R,2R,2a'R,4S,4'S,5S,6a'R,7a'R,9'R,9a'R,9b'R,10'R,13a'S,14a'S,14b'S)-4-羟基-3',3',5,9a',10',14a'-六甲基-4'-(((2S,3R,4S,5R)-3,4,5-三羟基四氢-2H-吡喃-2-基)氧基)十八氢-3,6-二氧杂螺[二环[3.1.0]己烷-2,12'-环丙[1',8a']萘[2',1':4,5]茚[2,1-b]吡喃]-9'-基 乙酸酯; (1R,2R,2a'R,4S,4'S,5S,6a'R,7a'R,9'R,9a'R,9b'R,10'R,13a'S,14a'S,14b'S)-4-Hydroxy-3',3',5,9a',10',14a'-hexamethyl-4'-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)octadecahydro-3,6-dioxaspiro[bicyclo[3.1.0]hexane-2,12'-cyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b]pyran]-9'-yl acetate; β-D-Xylopyranoside, (1'R,2S,4'S,4aR,5'S,5aR,7R,7aR,7bR,8R,10R,11aS,12aS,12bS,14aR)-7-(acetyloxy)hexadecahydro-4'-hydroxy-1,1,5',7a,8,12a-hexamethylspiro[5H-cyclopropa[1',8'a]naphth[2',1':4,5]indeno [2,1-b]pyran-10(2H),2'-[3,6]dioxabicyclo[3.1.0]hexan]-2-yl; (1'R,2S,4'S,4aR,5'S,5aR,7R,7aR,7bR,8R,10R,11aS,12aS,12bS,14aR)-4'-Hydroxy-1,1,5',7a,8,12a-hexamethyl-2-(β-D-xylopyranosyloxy)hexadecahydro-2H-spiro[cyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b] pyran-10,2'-[3,6]dioxabicyclo[3.1.0]hexan]-7-yl acetate; Shengmating; 26S-Actein; (-)-Actein; 9,19-Cyclolanostane-beta-D-xylopyranoside; 12β-Acetoxy-16,23:23,26:24,25-triepoxy-26-hydroxy-9,19-cyclo-5α-lanostan-3β-yl β-D-xylopyranoside
- 用途
- Actein 通过促进 ROS/JNK 活化和钝化人膀胱癌中的 AKT 途径来抑制细胞增殖，诱导自噬和凋亡，在体内几乎没有毒性，可作为生命科学研究的工具化合物及中草药成分。
