- 英文名称
- O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
- 分子式
- C11H16F6N5OP
- 分子量
- 379.25
- 中文别名
- HBTU试剂; O-(1H-苯并三唑-1-基)-N,N,N',N'-四甲基异脲六氟化磷; 苯并三唑-1-四甲基六氟磷酸酯; O-(苯并三唑-1-基)-N,N,N',N'-四甲基脲六氟磷酸盐; O-(苯并三唑-1-基)-N,N,N',N'-四甲基脲六氟磷酸季铵盐; O-苯并三氮唑-N,N,N',N'-四甲基脲鎓六氟磷酸盐; 苯并三氮唑-N,N,N',N'-四甲基脲六氟磷酸酯; N,N,N',N'-四甲基-O-(苯并三氮唑-1-基)硫脲六氟磷酸盐; HBTU; O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; [benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate; 1-(Bis(dimethylamino)methylene)-1H-benzo[d][1,2,3]triazole-1-ium 3-oxide hexafluorophosphate(V); N-[(1H-1,2,3-Benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methylmethanaminium hexafluorophosphate; N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate
- 用途
- 氨基酸保护剂；多肽合成用缩合剂。HBTU是酸胺缩合反应中鎓盐类缩合剂，价格比HATU便宜，比HBOT和EDCI组合贵，投料方法简单，缩合副产物为HOBT和TMU。可用作多肽合成偶联剂，具有极低消旋概率、反应条件简单、反应时间短、产率较高的优点。
