- 英文名称
- 2-{4-[2-(Methylsulfonyl)phenyl]-1-piperazinyl}-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one
- 分子式
- C18H22N4O3S2
- 分子量
- 406.52
- 中文别名
- G244-LM; G244-LM; 2-[4-(2-Methylsulfonylphenyl)piperazin-1-yl]-3,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one; 2-(4-(2-(methylsulfonyl)phenyl)piperazin-1-yl)-7,8-dihydro-3H-thiopyrano[4,3-d]pyrimidin-4(5H)-one; 2-[4-(2-methanesulfonylphenyl)piperazin-1-yl]-3H,4H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one; 2-(4-(2-(Methylsulfonyl)phenyl)piperazin-1-yl)-1,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one; 2-[4-(2-Methanesulfonyl-phenyl)-piperazin-1-yl]-3,5,7,8-tetrahydro-thiopyrano[4,3-d]pyrimidin-4-one; 2-[4-(2-methylsulfonylphenyl)piperazin-1-yl]-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one; G244 LM; G-244-LM; 2-[4-(2-methanesulfonylphenyl)piperazin-1-yl]-1H,4H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one
- 用途
- 化学合成；作为有效且特异的tankyrase 1/2抑制剂，可抑制Wnt信号传导。
