- 英文名称
- Imatinib-d8
- 分子式
- C29H23D8N7O
- 分子量
- 501.65
- 中文别名
- 伊马替尼D8; [2H8]-伊马替尼; 伊马替尼-D8同位素; Imatinib D8; STI 571; [2H8]-Imatinib; N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]benzamide; 4-(4-methyl-[2,2,3,3,5,5,6,6-D8]piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide; 4-{[4-Methyl(~2~H_8_)piperazin-1-yl]methyl}-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide; N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)benzamide; N-[4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methyl-piperazin-1-yl)methyl]benzamide; Imatinib Impurity 77
- 用途
- 示踪分析试剂；Imatinib D8 (STI571 D8) 是 Imatinib (STI571) 的氘代物，Imatinib 是口服生物可用的酪氨酸激酶抑制剂，可选择性抑制 BCR/ABL，v-Abl，PDGFR，c-kit 激酶活性。
