化合物T11546; 化合物HDHODH-IN-1; N-([1,1'-联苯]-4-基)-2-氰基-3-羟基丁-2-烯酰胺; 2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-; hDHODH IN 1; hDHODHIN1; N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide
用途
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with anti-inflammatory activity. As hDHODH is required for proliferating-cell viability, inhibitors like this compound eliminate hDHODH activity, associated with cancers, multiple sclerosis, and autoimmune/inflammatory diseases.
