- 英文名称
- (2E,4E)-N-((2S,5S)-5-(Hydroxymethyl)-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydrobenzo[e][1,4]diazocin-8-yl)-5-(4-(trifluoromethyl)phenyl)penta-2,4-dienamide
- 分子式
- C27H30F3N3O3
- 分子量
- 501.54
- 中文别名
- TPPB; 化合物TPPB; (2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-六氢-5-(羟基甲基)-1-甲基-2-(1-甲基乙基)-3-氧代-1,4-苯并二氮杂环辛四烯-8-基]-5-[4-(三氟甲基)苯基]-2,4-戊二烯酰胺; TPPB; (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide; (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide; (2E,4E)-N-[(2S,5S)-5-(Hydroxymethyl)-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide; (2S,5S)-(E,E)-8-(5-(4-(trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam; alpha-AMyloid Precursor Protein Modulator; α-Amyloid Precursor Protein Modulator
- 用途
- 化学合成；作为苯并内酰胺衍生的可渗透细胞的蛋白激酶C(PKC)活化物，Ki值为11.9nM；应储存在-20℃，溶入溶剂后尽量在一个月内使用
