- 英文名称
- (-)-Cyclocytidine hydrochloride
- 分子式
- C9H11N3O4·HCl
- 分子量
- 261.66
- 中文别名
- 盐酸环胞苷; 2,2'-Anhydro-1-β-D-arabinofuranosylcytosine hydrochloride; Cyclocytidine Hydrochloride; (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-iminiumchlorid; 2,2'-O-Cyclocytidine Hydrochloride; Ancitabine Hydrochloride; (2R,3R,3aS,9aR)-2-(Hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-3-ol hydrochloride (1:1); EINECS 233-515-6; MFCD00012636; 2,2'-Anhydro-(1-β-D-arabinofuranosyl)cytosine Hydrochloride; (-)-Cyclocytidine hydrochloride; (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-iminium chloride; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, (2R,3R,3aS,9aR)-, hydrochloride (1:1); 2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride; Ancitabine (hydrochloride)
- 用途
- 抗肿瘤药，对各种类型急性白血病及脑膜白血病均有效；生产滴眼液。不良反应和阿糖胞苷相似，但较轻，有骨髓抑制作用，白细胞、血小板减少，用量大时常出现腮腺痛，局部冷敷可使疼痛减轻，有时可见流涎、体位性低血压、结膜充血、鼻黏膜肿胀，个别病人出现头痛、皮疹，偶可引起一过性肺部炎症变化，用药期间应严格检查血象。
