- 英文名称
- Bisindolylmaleimide V
- 分子式
- C21H15N3O2
- 分子量
- 341.36
- 中文别名
- 双吲哚马来酰亚胺; 双吲哚马来酰亚胺 V; 3,4-二(1H-吲哚-3-基)-1-甲基-1H-吡咯-2,5-二酮; 1-甲基-3,4-双(1H-吲哚-3-基)马来酰亚胺; 3,4-双(1H-吲哚-3-基)-1-甲基-2,5-二氢-1H-吡咯-2,5-二酮; 1-Methyl-3,4-bis(indol-3-yl)maleimide; Ro 31-6045; 1-Methyl 3,4-bis(1H-indole-3-yl)-3-pyrroline-2,5-dione; 1-Methyl-3-(1H-indole-3-yl)-4-(1H-indole-3-yl)-1H-pyrrole-2,5-dione; 1-Methyl-3,4-bis(1H-indole-3-yl)-3-pyrroline-2,5-dione; 3,4-Bis(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione; 3,4-Bis(1H-indole-3-yl)-1-methyl-3-pyrroline-2,5-dione; 3,4-bis(1H-indol-3-yl)-1-methylpyrrole-2,5-dione; N-Methylbis(indol-3-yl)maleimide; 2,3-bis(1H-Indol-3-yl)-N-methylmaleimide; 3,4-Di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione; 3,4-bis(3-indolyl)-1-methyl-pyrrole-2,5-dione; 1-Methyl-3,4-bis(3-indolyl)maleimide; 1H-Pyrrole-2,5-dione,3,4-di-1H-indol-3-yl-1-methyl
- 用途
- 双吲哚马来酰亚胺V作为吲哚咔唑类衍生物，具有抗真菌、抗高血压、抗肿瘤和抑制血小板聚集等药理作用，其抗肿瘤活性作用靶点包括与细胞周期有关的多种激酶、细胞核拓扑异构酶以及与肿瘤细胞生长或凋亡有关的酶等，在生命科学领域用于相关药理研究与潜在药物开发。
