- 英文名称
- Carboprost tromethamine
- 分子式
- C25H47NO8
- 分子量
- 489.65
- 中文别名
- 卡前列腺氨丁三醇; (Z)-7-[(3R,5S)-3,5-二羟基-2-[(E,3S)-3-羟基-3-甲基辛-1-烯基]环戊基]庚-5-烯酸氨基丁三醇; 卡前列素丁三醇; 卡前列素氨丁三醇; (5Z,9α,11α,15E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid tris(hydroxymethyl)aminomethane salt; Carboprost TroMethaniMine; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1); (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl)-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1); (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1); (15S)-15-Methylprostaglandin F2a Tromethamine; Hemabate; Prostin/15M; Carboprost tromethamine salt; 15(S)15-Methyl pgf2a Tromethamine Salt; Carboprost trometamol; U 32921E
- 用途
- - 生物活性
Carboprost tromethamine 是前列腺素 F2α (prostaglandin F2α) 的 15 甲基类似物。Carboprost tromethamine 能有效促进子宫规律性收缩，显著减少产后出血量。
- 体内研究
Carboprost tromethamine has a significant effect on the prevention of postpartum hemorrhage in cesarean section, and has a significant effect on improving the state of hypercoagulable blood and maintaining the stable hemodynamic state. Carboprost tromethamine has been accounted for to be 84-96% successful in the treatment of persistent hemorrhage because of uterine atony.
