- 生物活性
Glufosinate 是谷氨酸的膦酸类似物，是一种由植物细胞转化为 PT (L-phosphinothricin) 的除草剂。Glufosinate 具有神经毒性作用。
- 体外研究
Glufosinate (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs).
Glufosinate (1-100 μM; 12DIV) significantly decreases
Celsr2
gene expression at 100 μM.
Glufosinate impairs ependymal cell capability to synthetize cilia.
- 体内研究
Glufosinate (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats.
The Elimination of Glufosinate (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats.
- 可用于果园、葡萄园、非耕地除草，也可用于马铃薯田
