- 英文名称
- 4,5-Dimethoxycanthin-6-one
- 分子式
- C16H12N2O3
- 分子量
- 280.28
- 中文别名
- 4,5-二甲氧基铁屎米酮; 苦木碱丁; 苦木丁碱; 甲基苦木酮碱; Nigakinon-methylether; Methyl nigakinone; 4,5-Dimethoxy-canthin-6-on; 4,5-Dimethoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one; 4,5-dimethoxy-6H-indolo[3,2,1-de]-1,5-naphthyridin-6-one; 4,5-Dimethoxy-6-oxo-6H-indolo<3.2.1-de><1.5>naphthyridin; 3,4-dimethoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one; 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one, 4,5-dimethoxy-; 4,5-dimethoxylcanthin-6-one; 14,15-dimethoxy-canthin-16-one; Methylnigakinone
- 用途
- 苦木碱丁是一种有效的、非竞争性的CYP1A2介导的phenacetin O-deethylation抑制剂，IC50值为1.7 μM，Ki值为2.6 μM。4,5-Dimethoxycanthin-6-one为生物碱，从Picrasma quassioides BENNET (Simaroubaceae)中分离得到。
