- 英文名称
- sulforhodamine 101
- 分子式
- C31H30N2O7S2
- 分子量
- 606.709
- 中文别名
- 磺酰罗丹明101*荧光参照标准*;磺基罗丹明101(99%);磺基罗丹明101 SULFORHODAMINE 101;磺基罗丹明101;SULFORHODAMINE 101游离态;9-(2,4-二磺基苯基)-2,3,6,7,12,13,16,17-八氢-1H,5H,11H,15H-氧杂蒽并[2,3,4-IJ:5,6,7-I'J']二喹嗪-18-鎓内盐;SULFORHODAMINE-101;SULFORHODAMINE-640;磺基罗丹明10; sulforhodamine; MFCD00012407; Sulforhodamine-101; EINECS 262-159-4; Texas Red,Sulforhodamine 101 Acid Chloride; 2-(2,3,6,7,12,13,16,17-octahydro-1h,5h,11h,15h-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium-9-yl)-5-sulfobenzenesulfonate
- 用途
- - 磺基罗丹明101为有机杂环有机物,可用作荧光标记染料。
- 生物活性
Sulforhodamine 101 (SR101) 是一种两性罗丹明红色荧光染料 (excitation/emission: 586/605 nm)。Sulforhodamine 101 被广泛用于研究神经元形态,并作为星形胶质细胞的细胞类型选择性荧光标记物,在体内和切片制备中都有应用。
- 体外研究
Sulforhodamine 101 (SR101) does not label astrocytes in brainstem slices as strong and specific as in the hippocampus or cortex. To minimize excitatory side effects, the concentration of Sulforhodamine 101 has to be kept as low as possible or the labeling procedure can be performed after the actual experiment.
- 体内研究
In vivo
, epileptic activity can be induced by intra-hippocampal injection of small volumes of 10 μM Sulforhodamine 101 or topical application of 100 μM.