- 英文名称
- Endothelin 1
- 分子式
- C109H159N25O32S5
- 分子量
- 2491.9
- 中文别名
- 内皮素1; H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH; (3S,6S,9S,12S,15S,18S)-3-((1H-咪唑-5-基)甲基)-18-((1H-吲哚-3-基)甲基)-1-((1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-氨基-7-(4-氨基丁基)-39-苄基-4-(2-羧乙基)-10-(羧甲基)-42-(4-羟基苄基)-19,22,28-三(羟甲基)-16-异丁基-45-异丙基-13-(2-(甲硫基)乙基)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-十四氧代-33,34,49,50-四硫杂-2,5,8,11,14,17,20,23,26,29,37,40,43,46-十四氮杂双环[23.22.4]五十一烷-36-基)-12,15-二((S)-仲丁基)-9-(羧甲基)-6-异丁基-1,4,7,10,13,16-六氧代-2,5,8,11,14,17-六氮杂十九烷-19-酸; Endothelin 1 (swine, human); CSCSSLMDKECVYFCHLDIIW; Endothelin-1 (human, porcine); ET-1; ET-1, HUMAN; ET-1, HUMAN AND PORCINE; ET-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT); ET-1 (HUMAN, MOUSE, RAT, PIG, BOVINE, DOG); ET-1, HUMAN, PORCINE; ET-1 (HUMAN, PORCINE, DOG, RAT); ENDOTHELIN-I, HUMAN, PORCINE; (3S,6S,9S,12S,15S,18S)-3-((1H-Imidazol-5-yl)methyl)-18-((1H-indol-3-yl)methyl)-1-((1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-42-(4-hydroxybenzyl)-19,22,28-tris(hydroxymethyl)-16-isobutyl-45-isopropyl-13-(2-(methylthio)ethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontan-36-yl)-12,15-di((S)-sec-butyl)-9-(carboxymethyl)-6-isobutyl-1,4,7,10,13,16-hexaoxo-2,5,8,11,14,17-hexaazanonadecan-19-oic acid
- 用途
- 内皮素1（ET-1）是具有人和猪内皮素1序列的合成肽，是有效的内源性血管收缩剂，通过ETA和ETB受体发挥作用，可引起血管平滑肌细胞纤维化、活性氧生成及促炎机制，用于研究内皮素1的生物活性及相关调节机制。
