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有机中间体及精细化学品

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(3R)-1-苄氧基羰基-3-甲基哌嗪
英文名称
Benzyl (3R)-3-methylpiperazine-1-carboxylate
CAS号
623586-00-5
分子式
C₁₃H₁₈N₂O₂
分子量
234.29
中文别名
(R)-4-Cbz-2-甲基哌嗪; (R)-4-苄氧羰基-2-甲基哌嗪; (R)-1-苄氧羰基-3-甲基哌嗪; 1-CBZ-(R)-3-甲基哌嗪; (R)-1-CBZ-3-甲基哌嗪; (R)-1-Cbz-3-methylpiperazine; (R)-Benzyl 3-methylpiperazine-1-carboxylate; Benzyl (3R)-3-methyl-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 3-methyl-, phenylmethyl ester, (3R)-; 4-N-BENZOXYCARBONYL-2-(R)-METHYLPIPERAZINE; 4-CBZ-(R)-2-METHYL PIPERAZINE; 4-BENZOXYCARBONYL-2-(R)-METHYLPIPERAZINE; (R)-4-CBZ-2-METHYLPIPERAZINE; (3R)-1-Benzyloxycarbonyl-3-methylpiperazine; (R)-4-Benzoxycarbonyl-2-methylpiperazine
用途
化学合成。
相关属性
基本信息物化属性
(3R)-3-[(叔丁氧羰基)氨基]哌啶-1-甲酸苄酯
英文名称
Benzyl (3R)-3-[(tert-butoxycarbonyl)amino]piperidine-1-carboxylate
CAS号
485820-12-0
分子式
C₁₈H₂₆N₂O₄
分子量
334.41
中文别名
(R)-1-CBZ-3-N-BOC-氨基哌啶; R-1-N-CBZ-3-BOC-氨基哌啶; (R)-1-CBZ-3-(BOC-氨基)哌啶; 苄基(R)-3-((叔丁氧基羰基)氨基)哌啶-1-羧酸酯; (R)-苯甲基 3-((叔-丁氧羰基)氨基)哌啶-1-甲酸基酯; (R)-3-((叔丁氧羰基)氨基)哌啶-1-甲酸苄酯; (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE; (3R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-piperidinecarboxylic acid phenylmethyl ester; (R)-1-Cbz-3-(Boc-aMino)piperidine; (R)-1-Cbz-3-N-Boc-aMinopiperidine; (R)-Benzyl 3-((Tert-Butoxycarbonyl)Amino)Piperidine-1-Carboxylate; (3R)-3-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-1-piperidinecarboxylic acid (phenylmethyl) ester; Benzyl (R)-3-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate; benzyl (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-1-carboxylate
用途

相关属性
基本信息物化属性
(3R)-3-甲基-4-(6-((2R)-2-((R)-S-甲基磺酰亚胺基)环丙基)-2-(1H-吡咯并[2,3-b]吡啶-4-基)嘧啶-4-基)吗啉
英文名称
Ceralasertib
CAS号
1352226-88-0
分子式
C₂₀H₂₄N₆O₂S
分子量
412.51
中文别名
4-[4-[1-[[S(R)]-S-甲基亚胺磺酰基]环丙基]-6-[(3R)-3-甲基-4-吗啉基]-2-嘧啶基]-1H-吡咯并[2,3-b]吡啶; AZD6738; 化合物Ceralasertib; (R)-3-甲基-4-[6-[1-[(R)-S-甲基磺酰亚胺基]环丙基]-2-(7-氮杂吲哚-4-基)-4-嘧啶基]吗啉; AZD6738; AZD-6738; (3R)-3-Methyl-4-(6-((2R)-2-((R)-S-methylsulfonimidoyl)cyclopropyl)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)morpholine; 4-[4-[1-[[S(R)]-S-Methylsulfonimidoyl]cyclopropyl]-6-[(3R)-3-methyl-4-morpholinyl]-2-pyrimidinyl]-1H-pyrrolo[2,3-b]pyridine; 4-{4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]-2-pyrimidinyl}-1H-pyrrolo[2,3-b]pyridine; (R)-imino(methyl)(1-(6-((R)-3-methylmorpholino)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)cyclopropyl)-lambda6-sulfanone
用途
化学合成；作为口服活性选择性ATR激酶抑制剂（IC50 1 nM），用于Phase 1/2临床研究；体外抑制Kras突变细胞系中ATR激酶活性及细胞活性，增强顺铂诱导ATM缺失细胞死亡；体内抑制肿瘤生长，与顺铂联用可使ATM缺失肿瘤快速退化，与放疗联用避免毒性并保持疗效。
相关属性
基本信息物化属性
(3R)-3-碘四氢呋喃
英文名称
(3R)-3-iodotetrahydrofuran
CAS号
873063-62-8
分子式
C₄H₇IO
分子量
198
中文别名
(R)-3-碘四氢呋喃; (3R)-3-碘氧杂环戊烷; Furan, tetrahydro-3-iodo-, (3R)-; (R)-3-Iodo-tetrahydrofuran; (3R)-3-Iodooxolane; (R)-3-Iodotetrahydrofuran
用途
化学合成。
相关属性
基本信息物化属性
(3R)-3-苄氧羰基氨基哌啶-1-甲酸叔丁酯
英文名称
tert-butyl (3R)-3-(phenylmethoxycarbonylamino)piperidine-1-carboxylate
CAS号
320580-76-5
分子式
C₁₈H₂₆N₂O₄
分子量
334.41
中文别名
1-BOC-(3R)-3-CBZ-氨基哌啶; R-1-BOC-3-CBZ-氨基哌啶; 叔丁基 (3R)-3-[[(苄氧基)羰基]氨基]哌啶-1-羧酸盐; (R)-3-(((苄氧基)羰基)氨基)哌啶-1-甲酸叔丁酯; tert-Butyl (3R)-3-{[(benzyloxy)carbonyl]amino}piperidine-1-carboxylate; 2-Methyl-2-propanyl (3R)-3-{[(benzyloxy)carbonyl]amino}-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)-; 1-N-Boc-3-(R)-cbz-amino-piperidine; (R)-tert-butyl 3-(benzyloxycarbonylamino)piperidine-1-carboxylate; (R)-1-Boc-(3-Cbz-aMino)piperidine; 1-Boc-(3R)-3-Cbz-aMinopiperidine; (R)-tert-butyl 3-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate; Tert-butyl (R)-3-(((benzyloxy)carbonyl)amino)piperidine-1-carboxylate
用途

相关属性
基本信息物化属性
(3R,4R)-(-)-D-赤酮酸内酯
英文名称
D-ERYTHRONOLACTONE
CAS号
15667-21-7
分子式
C₄H₆O₄
分子量
118.09
中文别名
D-赤酮酸内酯; (3R,4R)-3,4-二羟基二氢呋喃-2(3H)-酮; (3R-顺式)-(-)-二氢-3,4-二羟基-2(3H)-呋喃酮; D-三羟丁酸Γ-内酯; D-赤式-1,4-内酯; (2R,3R)-BUTANE-2,3,4-TRIOL-1,4 LACTONE; (3R)-CIS-4,5-DIHYDRO-3,4-DIHYDROXY-2(3H)-FURANONE; (3R-CIS)-(-)-DIHYDRO-3,4-DIHYDROXY-2(3H)-FURANONE; (3R,4R)-(-)-D-ERYTHRONOLACTONE; (3R,4R)-DIHYDROXYDIHYDRO-2(3H)-FURANONE; d-erythronic acid γ-lactone; D-ERYTHRONIC ACID GAMMA-LACTONE; (3R,4R)-3,4-Dihydroxydihydrofuran-2(3H)-one
用途
（3R,4R)-(-)-D-赤酮酸内酯主要用于医药领域，具体用途未在提供信息中详细说明。
相关属性
基本信息物化属性
(3R,4R)-1-苄基-4-(羟甲基)吡咯烷-3-醇
英文名称
(3R,4R)-1-Benzyl-4-(hydroxymethyl)pyrrolidin-3-ol
CAS号
253129-03-2
分子式
C₁₂H₁₇NO₂
分子量
207.27
中文别名
(3R,4R)-1-苄基-4-羟基-3-吡咯烷甲醇; (3R,4R)-1-Benzyl-4-hydroxy-3-pyrrolidinemethanol; (3R,4R)-1-Benzyl-4-(hydroxymethyl)-3-pyrrolidinol; 3-Pyrrolidinemethanol, 4-hydroxy-1-(phenylmethyl)-, (3R,4R)-
用途
化学合成。
相关属性
基本信息物化属性
(3R,4R)-1-苄基-N,4-二甲基哌啶-3-胺
英文名称
(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine
CAS号
477600-70-7
分子式
C₁₄H₂₂N₂
分子量
218.34
中文别名
(3R,4R)-1-苄基-3-甲氨基-4-甲基哌啶; (3R,4R)-1-苄基-4-甲基-3-甲氨基哌啶; (3R,4R)-N,4-二甲基-1-(苯基甲基)-3-哌啶胺; 顺式-1-苄基-4-甲基-3-甲氨基哌啶; (Cis)-Benzyl-N,4-dimethylpiperidin-3-amine; (3R,4R)-(1-benzyl-4-Methylpiperidin-3-yl)Methylamine; 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4R)-; (3R,4R)-1-Benzyl-N-Methyl-4-Methylpiperidin-3-amine
用途
托法替尼中间体
相关属性
基本信息物化属性
(3R,4R)-3,4-二甲基-4-(3-羟基苯基)哌啶
英文名称
(3R,4R)-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine
CAS号
119193-19-0
分子式
C₁₃H₁₉NO
分子量
205.3
中文别名
3-((3R,4R)-3,4-二甲基哌啶-4-基)苯酚; (3R,4R)-3-(3,4-二甲基-4-哌啶基)苯酚; (+)-(3R,4R)-3,4-二甲基-4-(3-羟基苯基)哌啶; 阿维莫泮中间体; (3R,4R)-3-(3,4-二甲基-4-呱啶基)苯酚; (+)-(3R,4R)-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine; 3-[(3R,4R)-3,4-dimethylpiperidin-4-yl]phenol; 3-((3R,4R)-3,4-DIMETHYLPIPERDIN-4-YL)PHENOL; (3R,4R)-3-(3,4-Dimethyl-4-piperidinyl)phenol; 3-(3,4-diMethylpiperidin-4-yl)phenol; (+)-(3R,4R)-DiMethyl-4-(3-hydroxyphenyl)piperidine; (3R-cis)-3-(3,4-diMethyl-4-piperidinyl)phenol; 3-[(3R,4R)-3,4-Dimethyl-4-piperidinyl]phenol
用途
爱维莫潘中间体。
相关属性
基本信息物化属性
(3R,4R)-3-氨基-4-羟基吡咯烷-1-甲酸叔丁酯
英文名称
(3R,4R)-tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
CAS号
330681-18-0
分子式
C₉H₁₈N₂O₃
分子量
202.25
中文别名
(3R,4R)-3-氨基-4-羟基吡咯烷-1-羧酸叔丁酯; REL-叔丁基(3R,4R)-3-氨基-4-羟基吡咯烷-1-羧酸酯; (3R,4R)-1-BOC-3-氨基-4-羟基吡咯烷; (3R,4R)-3-氨基-1-BOC-4-羟基吡咯烷; 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester,(3R,4R)-(9CI); (3R,4R)-4-aMino-1-N-Boc-3-hydroxypyrrolidine; Trans-(3R,4R)-1-Boc-3-aMino-4-hydroxypyrrolidine; rel-tert-Butyl (3R,4R)-3-amino-4-hydroxypyrrolidine-1-carboxylate; 1-Pyrrolidinecarboxylic acid, 3-amino-4-hydroxy-, 1,1-dimethylethyl ester, (3R,4R)-; (3R,4R)-3-Amino-1-Boc-4-hydroxypyrrolidine; trans-3-Amino-4-hydroxypyrrolidine-1-carboxylic acid tert-butyl ester; tert-butyl (3R,4R)-3-amino-4-hydroxypyrrolidine-1-carboxylate; 2-Methyl-2-propanyl (3R,4R)-3-amino-4-hydroxy-1-pyrrolidinecarboxylate
用途
化学合成。
相关属性
基本信息物化属性
(3R,4R)-N,4-二甲基-1-(苯基甲基)-3-哌啶胺盐酸盐
英文名称
(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
CAS号
1062580-52-2
分子式
C₁₄H₂₃ClN₂
分子量
254.8
中文别名
(3R,4R)-1-苄基-3-(甲氨基)-4-甲基哌啶双盐酸盐; 顺式-1-苄基-4-甲基-3-甲氨基-哌啶双盐酸盐; 托法替尼中间体A; (3R,4R)-1-苄基-N,4-二甲基哌啶-3-胺二盐酸盐; (3R,4R)-N,4-二甲基-1-(苯基甲基)-3-哌啶胺二盐酸盐; 托法替尼中间体; CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINE BIS-(HYDROCHLORIDE); cis-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride; cis-1-Benzyl-4-methyl-3-(methylamino)piperidine dihydrochloride; (3R,4R)-1-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE DIHYDROCHLORIDE; (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine BIS-(HYDROCHLORIDE); (3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine hydrochloride; 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-, hydrochloride (1:2)
用途
作为有机合成中间体和医药中间体，用于实验室及化工医药研发过程；作为原料药托法替尼中间体，用于治疗甲氨蝶呤反应不足或不耐受的中度至重度类风湿关节炎成年患者；用于制备janus激酶1选择性抑制剂；作为枸橼酸托法替尼（540737-29-9）的中间体
相关属性
基本信息物化属性
(3R,4R)-N1-BOC-4-氨基-3-羟基哌啶
英文名称
tert-butyl 4-amino-3-hydroxypiperidine-1-carboxylate
CAS号
203503-03-1
分子式
C₁₀H₂₀N₂O₃
分子量
216.28
中文别名
4-氨基-3-羟基哌啶-1-羧酸叔丁酯; 1-BOC-4-氨基-3-羟基哌啶; (3R,4r)-n1-boc-4-氨基-3-羟基哌啶; 1-Boc-4-amino-3-hydroxy-piperidine; 1-Piperidinecarboxylic acid, 4-aMino-3-hydroxy-, 1,1-diMethylethyl ester; tert-butyl 4-AMino-3-hydroxy-1-piperidinecarboxylate; 1,1-Dimethylethyl 4-amino-3-hydroxy-1-piperidinecarboxylate; tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate; N1-BOC-4-aMino-3-hydroxypiperidine; 1-Piperidinecarboxylic acid, 4-amino-3-hydroxy-, 1,1-dimethylethyl ester (9CI, ACI); tert-butyl trans(+-)-4-amino-3-hydroxypiperidine-1-carboxylate; tert-butyl (3R*,4R*)-4-amino-3-hydroxy-piperidine-1-carboxylate; 2-Methyl-2-propanyl 4-amino-3-hydroxy-1-piperidinecarboxylate
用途

相关属性
基本信息物化属性
(3R,4R)-rel-3-氟-4-(羟甲基)哌啶-1-羧酸叔丁酯
英文名称
(3R,4R)-rel-tert-Butyl 3-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate
CAS号
882033-94-5
分子式
C₁₁H₂₀FNO₃
分子量
233.28
中文别名
(3R,4R)-rel-3-氟-4-(羟甲基)哌啶-1-羧酸叔丁基叔丁酯; (3S,4S)-rel-1-Boc-3-氟-4-(羟甲基)哌啶; (3R,4R)-rel-1-Boc-3-氟-4-哌啶基甲醇; (3S,4S)-rel-1-Boc-3-fluoro-4-(hydroxymethyl)piperidine; (3,4)-trans-tert-butyl 3-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate; rel-(3S,4S)-1-Boc-3-fluoro-4-(hydroxymethyl)piperidine; 1-Piperidinecarboxylic acid, 3-fluoro-4-(hydroxymethyl)-, 1,1-dimethylethyl ester, (3R,4R)-rel-; tert-butyl trans-3-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate; (3R,4R)-rel-1-Boc-3-fluoro-4-(hydroxymethyl)piperidine
用途

相关属性
基本信息物化属性
(3R,4R)-rel-3-氟四氢-2H-吡喃-4-胺盐酸盐
英文名称
(3R,4R)-rel-3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride
CAS号
1630906-37-4
分子式
C₅H₁₁ClFNO
分子量
155.6
中文别名
顺式-3-氟代-4-胺盐酸盐; 顺式3-氟代氧杂-4-胺盐酸盐; 顺-3-氟噁烷-4-胺盐酸; 顺式-3-氟四氢-2H-吡喃-4-胺盐酸盐; cis-3-Fluorooxan-4-amine hydrochloride; cis-2H-Pyran-4-amine, 3-fluorotetrahydro- hydrochloride; cis-3-fluorooxan-4-amine, hydrochloride; cis-3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride; CIS-3-FLUORO-TETRAHYDRO-2H-PYRAN-4-AMINE HCL; rel-(3R,4R)-3-Fluorooxan-4-amine hydrochloride; 2H-Pyran-4-amine, 3-fluorotetrahydro-, hydrochloride (1:1), (3R,4R)-rel-; 3-fluoro tetrahydro-2H-pyran-4amine hcl; (3R,4R)-3-fluorooxan-4-amine hydrochloride; (3R,4R)-3-Fluorotetrahydro-2H-pyran-4-amine hydrochloride; (3R,4R)-3-Fluorotetrahydropyran-4-amine HCl; Cis-3-Fluoro-tetrahydro-2H-pyran-4-amine hydrochloride
用途
化学合成。
相关属性
基本信息物化属性
(3R,4R)-吡咯烷-3,4-二醇
英文名称
(3R,4R)-Pyrrolidine-3,4-diol
CAS号
186393-31-7
分子式
C₄H₉NO₂
分子量
103.12
中文别名
(3R,4r)-3,4-吡咯烷二醇; trans-3,4-二羟基吡咯烷; (R,R)-pyrrolidine-3,4-diol; (3R,4R)-dihydroxypyrrolidine; trans-3,4-Dihydroxypyrrolidine; (3R),(4R)-pyrrolidinediol; (3R,4R)-3,4-PYRROLIDINEDIOL; 1,4-imino-1,4-dideoxy-D-threitol; (-)-(3R,4R)-3,4-dihydroxypyrrolidine; 3,4-Pyrrolidinediol,(3R,4R); Trans-3,4-pyrrolidinediol; trans-pyrrolidine-3,4-diol; (3R,4R)-3,4-dihydroxypyrrolidine
用途
化学合成。
相关属性
基本信息物化属性
(3R,4R,5R)-5-甲基四氢呋喃-2,3,4-三乙酸三酯
英文名称
tri-O-acetyl-5-deoxy-D-ribofuranose
CAS号
37076-71-4
分子式
C₁₁H₁₆O₇
分子量
260.24
中文别名
5-脱氧-D-呋喃核糖 1,2,3-三乙酸酯; 三-o-乙酰基-5-脱氧-d-呋喃核糖; 5-Deoxy-D-ribofuranose 1,2,3-triacetate; 1,2,3-Tri-O-acetyl-5-deoxyribose; 5-Deoxy-D-ribofuranose triacetate; 1,2,3-Triacety1-5-deoxy-beta-D-ribofuranose; (3R,4R,5R)-5-Methyltetrahydrofuran-2,3,4-triyl triacetate; 1,2,3-Tri-O-acetyl-5-deoxy-D-ribofuranoside; 5-desoxy-1,2,3-tri-O-acetyl-D-ribofuranose; 5-deoxy-1,2,3-tri-O-acetyl-D-ribofuranose; 5'-deoxyribofuranose 1,2,3-triacetate; 5-deoxy-D-ribose-1,2,3-tri-O-acetate; 1,2,3-Tri-O-acetyl-5-deoxyribofuranose
用途

相关属性
基本信息物化属性
(3R,4S)-3-((苯并[d][1,3]间二氧杂环戊烯-5-基氧基)甲基)-4-(4-氟苯基)哌啶盐酸盐
英文名称
ent-Paroxetine Hydrochloride
CAS号
130855-30-0
分子式
C₁₉H₂₁ClFNO₃
分子量
365.83
中文别名
帕罗西汀相关物质C; 帕罗西汀杂质D; (+)-反式-帕罗西汀盐酸盐; 帕罗西汀相关化合物C; 帕罗西汀USP RC C; 帕罗西汀对映异构体; ENT盐酸帕罗西汀; (3R,4S)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride; Paroxetine impurity D; (3R,4S)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine hydrochloride; (+)-trans-Paroxetine Hydrochloride; Paroxetine hydrochloride, (+)-; Paroxetine hydrochloride, trans-(+)-; Paroxetine EP Impurity D HCl; Paroxetine Hydrochloride Anhydrous EP Impurity D; Paroxetine Hydrochloride Hemihydrate EP Impurity D
用途
药物分析标准。
相关属性
基本信息物化属性
(3R,4S)-3-(三乙基硅氧基)-4-苯基-2-氧-氮杂环丁-1-甲酸叔丁酯
英文名称
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate
CAS号
149198-47-0
分子式
C₂₀H₃₁NO₄Si
分子量
377.55
中文别名
(3R,4S)-2-氧代-4-苯基-3-((三乙基硅烷基)氧)氮杂环丁烷-1-羧酸叔丁酯; (3R,4S)-叔丁基 2-氧代-4-苯基-3-(三乙基硅氧基)氮杂环丁-1-羧酸酯; (3R,4S)-2-氧代-4-苯基-3-[(三乙基硅基)氧]氮杂环丁烷-1-羧酸叔丁酯; N-叔丁氧羰基-3-(三乙基硅基)-4-苯基-2-吖叮啶酮; 多西四元环; (3R,4S)-1-叔丁氧基羰基-3-三乙基硅氧基-4-苯基-2-丙内酰胺; 多烯紫杉醇侧链; 多西他塞侧链; (3R,4S)-1-叔丁氧羰基-3-三乙基硅氧基-4-苯基-2-氮杂环丁酮; 2-oxo-4-phenyl-3-triethylsilyloxy-1-azetidinecarboxylic acid tert-butyl ester; DOCETAXEL SIDE CHAIN NO 2; (3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone; (3R-cis)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester; (3r,4s)-1-Azetidine Carboxylic Acid-2-Oxo-4-Phenyl-3-[(Triethylsilyl)Oxy]-1,1-Dimethyl Ethyl Ester; tert-Butyl (3R,4S)-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine-1-carboxylate; 2-Methyl-2-propanyl (3R,4S)-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylate; Docetaxel Impurity 9; cis-tert-Butyl 2-oxo-4-phenyl-3-((triethylsilyl)oxy)azetidine-1-carboxylate; (3R,4S)-1-Boc-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine; (3R, 4S)-1-t-Butoxycarbonyl-4-phenyl-3-triethylsilyloxy-2-azetidinone
用途
作为重要医药中间体，用于制备多西他赛（抗肿瘤药微管抑制剂）；同时作为有机合成中间体和医药中间体，用于实验室研发过程和化工医药合成过程中。
相关属性
基本信息物化属性
(3R,4S)-3-(三乙基硅氧基)-4-苯基-2-氧-氮杂环丁-1-甲酸叔丁酯
英文名称
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate
CAS号
149198-47-0
分子式
C₂₀H₃₁NO₄Si
分子量
377.55
中文别名
(3R,4S)-叔丁基 2-氧代-4-苯基-3-(三乙基硅氧基)氮杂环丁-1-羧酸酯; (3R,4S)-2-氧代-4-苯基-3-[(三乙基硅基)氧]氮杂环丁烷-1-羧酸叔丁酯; N-叔丁氧羰基-3-(三乙基硅基)-4-苯基-2-吖叮啶酮; 多西四元环; (3R,4S)-1-叔丁氧基羰基-3-三乙基硅氧基-4-苯基-2-丙内酰胺; 多烯紫杉醇侧链; 多西他塞侧链; (3R,4S)-1-叔丁氧羰基-3-三乙基硅氧基-4-苯基-2-氮杂环丁酮; 2-oxo-4-phenyl-3-triethylsilyloxy-1-azetidinecarboxylic acid tert-butyl ester; DOCETAXEL SIDE CHAIN NO 2; (3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone; (3R-cis)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester; (3r,4s)-1-Azetidine Carboxylic Acid-2-Oxo-4-Phenyl-3-[(Triethylsilyl)Oxy]-1,1-Dimethyl Ethyl Ester; (3R,4S)-1-AZETIDINECARBOXYLIC ACID 2-OXO-4-PHENYL-3-[(TRIETHYLSILY)OXY]-1,1-DIMETHYLETHYL ESTER; tert-Butyl (3R,4S)-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine-1-carboxylate; tert-butyl (3R,4S)-2-oxo-4-phenyl-3-triethylsilyloxyazetidine-1-carboxylate; 2-Methyl-2-propanyl (3R,4S)-2-oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylate
用途
作为重要的医药中间体用于制备多西他赛；作为有机合成中间体和医药中间体用于实验室研发过程和化工医药合成过程中
相关属性
基本信息物化属性
(3R,4S)-3-氟-4-羟基吡咯烷-1-羧酸叔丁酯
英文名称
(3R,4S)-1-Boc-3-fluoro-4-hydroxypyrrolidine
CAS号
1174020-49-5
分子式
C₉H₁₆FNO₃
分子量
205.23
中文别名
(3R,4S)-3-氟-4-羟基-1-吡咯烷羧酸叔丁酯; (3R,4S)-1-BOC-3-氟-4-羟基吡咯烷; 叔-丁基 (3R,4S)-3-氟-4-羟基吡咯烷-1-甲酸基酯; (3S,4R)-1-BOC-4-氟吡咯烷-3-醇; tert-Butyl cis-3-fluoro-4-hydroxypyrrolidine-1-carboxylate; tert-Butyl (3R,4S)-3-fluoro-4-hydroxypyrrolidine-1-carboxylate; (3R,4S)-3-Fluoro-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; (3R,4S)-tert-butyl 3-fluoro-4-hydroxypyrrolidine-1-carboxylate; 1-Pyrrolidinecarboxylic acid, 3-fluoro-4-hydroxy-, 1,1-dimethylethyl ester, (3R,4S)-; (3R,4S)-3-Fluoro-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester; (3S,4R)-1-Boc-4-fluoropyrrolidin-3-ol; cis-tert-Butyl 3-fluoro-4-hydroxypyrrolidine-1-carboxylate; cis (1-Boc)-3-fluoro-4-hydroxypyrrolidine
用途

相关属性
基本信息物化属性

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