- 英文名称
- Alexidine dihydrochloride
- 分子式
- C26H58Cl2N10
- 分子量
- 581.71
- 中文别名
- 己联双辛胍二盐酸盐; N,N''-双(2-乙基己基)-3,12-二亚氨基-2,4,11,13-四氮杂十四烷二亚胺二盐酸盐; N1,N14-二(2-乙基己基)-3,12-二亚胺-2,4,11,13-四氮杂十四烷二脒盐酸盐(1:2); N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide dihydrochloride; N,N''''-1,6-Hexanediylbis[N'-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride; n,n''''-hexane-1,6-diylbis[n'-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride; Imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(2-ethylhexyl)-, hydrochloride (1:2); Bisguadine; alexidine 2HCl; 1,1'-Hexamethylene-bis(5-[2-ethylhexyl]biguanide); QR-711; Bisguanidine; Compound-904; 1-[N'-[6-[[amino-[[N'-(2-ethylhexyl)carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-(2-ethylhexyl)guanidine;dihydrochloride; ALEXIDINE HYDROCHLORIDE; Alexidine HCl; 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride; 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2); 1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride; Alexidine (dihydrochloride)
- 用途
- 化学合成；生命科学领域广谱抑菌、杀菌，用于漱口液治疗口腔疾病；作为保健品化妆品原料（甜味剂前体）；Alexidine dihydrochloride 是抗癌剂，靶向线粒体酪氨酸磷酸酶 PTPMT1 诱导线粒体凋亡，对多种真菌病原体（如念珠菌、隐球菌、曲霉）有抗真菌和抗生物膜活性，可抑制浮游生长和成熟生物膜，用于抗真菌药物研究。
