- 英文名称
- DOTATATE acetate
- 分子式
- C67H94N14O21S2
- 分子量
- 1495.69
- 中文别名
- 2,2',2''-(10-(2-(((R)-1-(((4R,7S,10S,13R,16S,19R)-13-((1H-吲哚-3-基)甲基)-10-(4-氨基丁基)-4-(((1S,2R)-1-羧基-2-羟丙基)氨基甲酰基)-16-(4-羟基苄基)-7-((R)-1-羟乙基)-6,9,12,15,18-五氧代-1,2-二硫杂-5,8,11,14,17-五氮杂环二十烷-19-基)氨基)-1-氧代-3-苯基丙-2-基)氨基)-2-氧代乙基)-1,4,7,10-四氮杂环十二烷-1,4,7-三基)三乙酸乙酸盐; N-[[4,7,10-三(羧甲基)-1,4,7,10-四氮杂环十二碳-1-基]乙酰基]-D-苯丙氨酰-L-半胱氨酰-L-酪氨酰-D-色氨酰-L-赖氨酰-L-苏氨酰-L-半胱氨酰-L-苏氨酸环(2-7)-二硫醚乙酸盐; DOTA-(Tyr3)-Octreotate; 4,7,10-tricarboxymethyl-1,4,7,10-tetraaza-cyclododecan-1-yl-acetyl-d-phe-cys-tyr-d-trp-lys-thr-cys-thr-oh, (disulfide bond) acetate; DOTA-(TYR3)-OCTREOTATE ACETATE; DOTA-(TYR3,THR8)-OCTREOTIDE ACETATE; N-[[4,7,10-Tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threonine cyclic (2-7)-disulfide acetate (salt)
- 用途
- 作为DOTA偶联肽，可被放射性核素标记用于正电子发射断层扫描(PET)成像和肽受体放射性核素治疗(PRRT)，177Lu-DOTATATE在大鼠中显示出优异抗肿瘤效果。
