综合文献
Controlled IterativeCross‐Coupling: On the Way to the Automation ofOrganic Synthesis
- 发布日期
- 作者
- Congyang Wang; Frank Glorius; Congyang Wang Dr.; Frank Glorius Prof. Dr.
摘要
Repetition does not hurt! New strategies for the modulation of the reactivity of difunctional building blocks are discussed, allowing the palladium-catalyzed controlled iterative cross-coupling and, thus, the efficient formation of complex molecules of defined size and structure (see scheme). As in peptide synthesis, this development will enable the automation of these reactions. M PG =protected metal, M act =metal.