- 英文名称
- Sodium Tauroglycocholate
- 分子式
- C28H47N2NaO8S
- 分子量
- 594.74
- 中文别名
- 甘牛胆酸钠; 3α,7α,12α-三羟基-5β-胆烷酸钠; 2-(2-((R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-三羟基-10,13-二甲基十六烷基-1H-环戊[a]菲基-17-基)戊酰胺基)乙酰胺基)-1-磺酸钠盐; Sodium glycotaurocholate; sodium,2-[[2-[[(4R)-4-[(3R,5S,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetyl]amino]ethanesulfonate; Sodium 2-({N-[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycyl}amino)ethanesulfonate; Ethanesulfonic acid, 2-[[2-[[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]acetyl]amino]-, sodium salt (1:1); Ethanesulfonic acid, 2-(((((3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)acetyl)amino)-, monosodium salt; sodium N-(N-choloylglycyl)taurinate; 2-[[[[(3a,5b,7a,12a)-3,7,12-Trihydroxy-24-oxocholan-24-yl]amino]acetyl]amino]-ethanesulfonic acid monosodium salt; 2-[[[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]acetyl]amino]ethanesulfonic acid sodium salt
- 用途
- 生命科学领域用于肠道菌选择性培养基的配制；作为肝细胞胆酸运输系统的抑制剂；用作化学渗透促进剂的表面活性剂；通过激活核受体FXR和膜受体TGR5调节葡萄糖和脂质代谢，影响脂肪、葡萄糖和能量代谢相关基因。
