588691-24-1 2'-O-甲基-5'-O-(4,4'-二甲氧基三苯甲基)-5-碘代尿苷

名称和标识

中文名: 2'-O-甲基-5'-O-(4,4'-二甲氧基三苯甲基)-5-碘代尿苷
英文名: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine
CAS号: 588691-24-1
分子式: C31H31IN2O8
分子量: 686.49
中文别名: 5-O-[双(4-甲氧基苯基)苯基甲基]-5-碘-2-O-甲基-尿苷; 5'-O-[二(4-甲氧基苯基)苯基甲基]-5-碘-2'-O-甲基尿苷; 5-碘-5'-O-DMT-2'-甲氧基尿苷; 5'-O-(二甲氧基三苯甲基)-5-碘-2'-O-甲基尿苷; 1-((2R,3R,4R,5R)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-羟基-3-甲氧基四氢呋喃-2-基)-5-碘嘧啶-2,4(1H,3H)-二酮; 2'-(O)-甲基-5'-(O)-二甲氧基三苯甲基-5-碘尿苷
英文别名: 5'-O-DMT-5-I-2'-OMe-rU; 5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLURIDINE; 5'-O-(DMT)-5-IODO-2'-O-METHYLURIDINE; 2'-O-Methyl-5'-O-DMT-5-iodouridine; Uridine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-5-iodo-2'-O-Methyl-; 2'-O-Methyl-5'-O-DMTr-5-iodouridine; 5-I-DMT-2'-O-Me-Ur; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl- (9CI); 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione

用途与制备

作为嘌呤核苷类似物，具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤；通过抑制DNA合成、诱导细胞凋亡发挥抗癌作用

医药

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