- BBB permeant
- Yes
- Bioavailability Score
- 0.85
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- GI absorption
- High
- Log K p (skin permeation)
- -7.01 cm/s
- Log S (Ali)
- -1.68
- Log S (ESOL)
- -1.91
- Log S (SILICOS-IT)
- -2.27
- LogP
- 1.49750
- Molar Refractivity
- 62.83
- Num. H-bond acceptors
- 3.0
- Num. H-bond donors
- 1.0
- Num. heavy atoms
- 16
- Num. rotatable bonds
- 2
- P-gp substrate
- No
- PSA
- 57.61 Ų
- Synthetic accessibility
- 2.08
- 储存条件
- 室温
- 密度
- 1.297±0.06 g/cm³ (Predicted)
- 水溶解性
- 2.73 mg/ml ; 0.0124 mol/l
- 沸点
- 522 °C (760 mmHg)
- 熔点
- 152-153 °C
- 精确质量
- 219.09000
- 酸度系数(pKa)
- 4.42±0.20 (Predicted)
- 闪点
- 269.5 °C