304464-97-9 8-去甲基伊伐布雷定

名称和标识

中文名: 8-去甲基伊伐布雷定
英文名: 8-Demethyl Ivabradine
CAS号: 304464-97-9
分子式: C26H34N2O5
分子量: 454.56
中文别名: 伊伐布雷定杂质K; 伊伐布雷定杂质E; 伊伐布雷定杂质32; 8-O-去甲基伊伐布雷定; 盐酸伊伐布雷定杂质S33174; 伊伐布雷定杂质S33174
英文别名: 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7-hydroxy-8-methoxy-2,5-dihydro-1H-3-benzazepin-4-one; 3-{3-[{[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-8-hydroxy-7-methoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-8-hydroxy-7-methoxy-2H-3-benzazepin-2-one; 8-O-Desmethyl Ivabradine Hydrochloride; Ivabradine Impurity k; Ivabradine 8-O-Desmethyl Impurity; Ivabradine Impurity E (8-Demethyl Ivabradine)

用途与制备

作为伊伐布雷定的代谢物；伊伐布雷定是具有口服活性的超极化激活的环核苷酸门控离子通道（HCN）通道阻滞剂。

医药

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