- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- Brenk
- 0.0 alert
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Egan
- 0.0
- Fraction Csp3
- 0.36
- GI absorption
- High
- Leadlikeness
- 1.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -8.27 cm/s
- Log S (Ali)
- 0.27
- Log S (ESOL)
- -0.39
- Log S (SILICOS-IT)
- -2.66
- LogP
- 2.84180
- Molar Refractivity
- 55.27
- Muegge
- 1.0
- Num. H-bond acceptors
- 3.0
- Num. H-bond donors
- 2.0
- Num. arom. heavy atoms
- 6
- Num. heavy atoms
- 14
- Num. rotatable bonds
- 4
- P-gp substrate
- No
- PAINS
- 0.0 alert
- PSA
- 63.32 Ų
- Synthetic accessibility
- 1.84
- Veber
- 0.0
- 储存条件
- 室温，避光，保存于惰性气体中
- 密度
- 1.135±0.06 g/cm³ (Predicted)
- 水溶解性
- 78.4 mg/ml ; 0.406 mol/l
- 沸点
- 377.3 °C (760 mmHg)
- 精确质量
- 229.086960
- 蒸汽压
- 2.31E-06 mmHg (25 °C)
- 酸度系数(pKa)
- 3.78±0.10 (Predicted)
- 闪点
- 182 °C
