2-苯基-1,2,3,4-四氢异喹啉可作为有机合成中间体和医药中间体，主要用于实验室研发过程和化工生产过程中。
医药;化工
路线1：钯催化芳基化法
- 步骤：向2-mL Biotage微波瓶中加入Pd(OAc)₂（5.6mg，5mol%）、CyJohnPhos（9.6mg，5.5mol%）、KOt-Bu（78.4mg，1.4当量）和芳基碘（0.5mmol，1当量）（固体先加）；密封后氩气吹扫，加入叔丁醇（1.0mL）、液体芳基碘（0.5mmol，1当量）和1,2,3,4-四氢异喹啉（75mL，1.2当量）；100℃微波照射5分钟，冷却后用EtOAc稀释，硅藻土过滤，滤液经饱和NaCl洗涤、MgSO₄干燥、减压浓缩得粗产物。
- 条件：以叔丁醇为溶剂，Pd(OAc)₂/CyJohnPhos为催化剂，KOt-Bu为碱，100℃微波反应5分钟，惰性气氛。
- 收率：94%
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