170082-17-4 3'-羟基康力龙D3

Safety and Hazards / Hazards Identification / GHS Classification / Signal: Danger Safety and Hazards / Hazards Identification / GHS Classification / GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H301: Toxic if swallowed [Danger Acute toxicity, oral]; H311: Toxic in contact with skin [Danger Acute toxicity, dermal]; H331: Toxic if inhaled [Danger Acute toxicity, inhalation]; H370 **: Causes damage to organs [Danger Specific target organ toxicity, single exposure] Safety and Hazards / Hazards Identification / GHS Classification / Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P308+P316, P316, P321, P330, P361+P364, P370+P378, P403+P233, P403+P235, P405, and P501 Safety and Hazards / Hazards Identification / GHS Classification / Note: This chemical does not meet GHS hazard criteria for < 0.1% (4 of 7623) of reports. Safety and Hazards / Hazards Identification / GHS Classification / Signal: Danger Safety and Hazards / Hazards Identification / GHS Classification / GHS Hazard Statements: H225 (> 99.9%): Highly Flammable liquid and vapor [Danger Flammable liquids]; H301 (99.9%): Toxic if swallowed [Danger Acute toxicity, oral]; H311 (99.9%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H331 (99.4%): Toxic if inhaled [Danger Acute toxicity, inhalation]; H370 (> 99.9%): Causes damage to organs [Danger Specific target organ toxicity, single exposure] Safety and Hazards / Hazards Identification / GHS Classification / Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P308+P316, P316, P321, P330, P361+P364, P370+P378, P403+P233, P403+P235, P405, and P501 Safety and Hazards / Hazards Identification / GHS Classification / ECHA C&L Notifications Summary: Aggregated GHS information provided per 7623 reports by companies from 149 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 4 of 7623 reports by companies.; There are 148 notifications provided by 7619 of 7623 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Safety and Hazards / Hazards Identification / GHS Classification / Signal: Danger Safety and Hazards / Hazards Identification / GHS Classification / GHS Hazard Statements: H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]; H360FD (100%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Safety and Hazards / Hazards Identification / GHS Classification / Precautionary Statement Codes: P203, P280, P318, P405, and P501 Safety and Hazards / Hazards Identification / GHS Classification / ECHA C&L Notifications Summary: The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. Safety and Hazards / Hazards Identification / GHS Classification / Signal: Danger Safety and Hazards / Hazards Identification / GHS Classification / GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Safety and Hazards / Hazards Identification / GHS Classification / Precautionary Statement Codes: P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P330, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 Safety and Hazards / Hazards Identification / GHS Classification / Signal: Danger Safety and Hazards / Hazards Identification / GHS Classification / GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H303: May be harmful if swallowed [Warning Acute toxicity, oral]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure;

甲醇主要用作工业溶剂（如油墨、树脂、染料），医药中间体（胆固醇、维生素等合成），汽车防冻剂、汽油添加剂，燃料（野餐炉、替代燃料），涂料/清漆去除剂，半导体制造清洗/干燥，液压压裂液中作腐蚀抑制剂和摩擦减阻剂，化妆品中作溶剂和变性剂，食品中作提取溶剂，实验室高纯度试剂（如光谱级）。

溶剂; 燃料; 防冻剂; 化工中间体; 医药原料; 农药原料; 涂料添加剂; 半导体制造; 印刷油墨; 液压压裂液添加剂; 化妆品原料; 食品添加剂（提取溶剂）; 实验室试剂

工业合成法（主流）

• 路线1：合成气催化转化
  • 原料：合成气（H₂与COx混合气体）
  • 工艺：低压法（5-10 MPa），采用铜基催化剂
  • 步骤：合成气压缩、预热后进入反应器，经催化反应生成甲醇；产物经冷凝分离，非凝气循环，粗甲醇蒸馏提纯
  • 特点：克服平衡限制，投资及生产成本低，操作灵活

其他方法（历史/实验）

• 木馏油蒸馏：早期从木材干馏中提取（现工业应用少）
• 天然气部分氧化：以甲烷为原料，经部分氧化制合成气后转化
• 甲烷-钼催化剂法：实验阶段，未工业化