203737-93-3 伊司他肟

运输信息：冰袋运输。危险描述：非危险化学品。

Istaroxime (PST2744) is a positive inotropic compound through inhibition of Na+,K+-ATPase. In vitro: inhibits dog kidney Na+/K+-ATPase with IC50 0.43±0.15 μM, guinea pig kidney IC50 8.5 μM. In vivo: induces progressive +dP/dt max increase, reaching 80% (ED80) at 1.89±0.37 mg/kg and peak 140±3.5% at 4.88±0.6 mg/kg.

生命科学