201422-03-9 肉豆蔻酰化PKI 14-22酰胺

名称和标识

中文名: 肉豆蔻酰化PKI 14-22酰胺
英文名: PKI 14-22 amide, myristoylated
CAS号: 201422-03-9
分子式: C53H100N20O12
分子量: 1209.49
中文别名: (S)-N1-((S)-1-(((2S,3S)-1-氨基-3-甲基-1-氧代戊烷-2-基)氨基)-1-氧代丙烷-2-基)-2-((2S,5S,11S,14S)-2,5,14-三(3-胍基丙基)-11-((R)-1-羟乙基)-4,7,10,13,16,19-六氧代-3,6,9,12,15,18-六氮杂三十二烷酰胺)琥珀酰胺
英文别名: protein kinase a inhibitor 14-22 amide, cell-permeable, myristoylated; pki 14-22 amide, cell-permeable; myristoylated protein kinase a inhibitor amide 14-22, cell-permeable; myr-grtgrrnai-nh2; pki 14-22 amide, myristoylated; (2S)-N-[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[[(2S,3R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(tetradecanoylamino)acetyl]amino]pentanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]pentanoyl]amino]pentanoyl]amino]butanediamide; GRTGRRNAI; L-Isoleucinamide,N-(1-oxotetradecyl)glycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl-; myr-PKI; MYRISTOYLATED PKI (14-22) AMIDE

用途与制备

PKI 14-22 amide,myristoylated 是一种有效的 cAMP 依赖性 PKA 抑制剂；可降低 IgG 介导的吞噬反应；可抑制中性粒细胞粘附。

医药

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