1384268-04-5 (E)-1-(5-羟基-2,2-二甲基-2H-苯并吡喃-6-基)-3-(噻吩-2-基)丙-2-烯-1-酮

运输信息：冰袋运输。危险描述：非危险化学品。

SYP-5 is a Hypoxia-inducible factor-1 (HIF-1) inhibitor, inhibits tumor cell migration and invasion, tumor angiogenesis; downregulates VEGF and MMP-2; suppresses hypoxia-induced HIF-1 upregulation and downstream gene expression in Hep3B/Bcap37 cells; inhibits angiogenesis in tube formation assay; retards cell migration/invasion induced by hypoxia/FBS; specifically inhibits hypoxic induction of luciferase in U251-HRE.

生命科学