101246-66-6 苯丝氨酸

运输方式：冰袋运输。危险描述：非危险化学品（部分来源）；皮肤刺激（类别2）、严重眼刺激（类别2）、呼吸道刺激（特异性靶器官毒性-一次接触，类别3）。WGK Germany:3，RTECS号:UY8586000，存储类别:11 - 可燃固体。防护措施：P261、P264、P264+P265、P271、P280、P302+P352、P304+P340、P305+P351+P338、P319、P321、P332+P317、P337+P317、P362+P364、P403+P233、P405、P501。

Phenserine is a derivative of Physostigmine, an effective non-competitive, long-acting, and selective AChE inhibitor. It reduces β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ) formation, improves cognitive ability, and alleviates Alzheimer's disease progression. In vitro: 1-25 μM for 48 hours in CHO APP 751SW cells shows 18.6% reduction at 10 μM and 51.4% reduction at 25 μM. In vivo: 1-4 mg/kg intraperitoneal injection for 4 days in male Fischer-344 rats improves learning and spatial memory in scopolamine-induced impairment.

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