1000700-26-4 ATB-343

中文名称: ATB-343
英文名称: 4-(3-Thioxo-3H-1,2-dithiol-5-yl)phenyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
CAS号
分子式: C₂₈H₂₀ClNO₄S₃
分子量: 566.11
更新日期: 2026-06-23

名称和标识

中文名: ATB-343
英文名: 4-(3-Thioxo-3H-1,2-dithiol-5-yl)phenyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
CAS号: 1000700-26-4
分子式: C28H20ClNO4S3
分子量: 566.11
英文别名: [4-(5-sulfanylidenedithiol-3-yl)phenyl] 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate; 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester; ATB 343; [4-(5-thioxodithiol-3-yl)phenyl] 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetate; 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester-1H-indole-3-acetic acid; 4-(3-Sulfanylidene-3H-1,2-dithiol-5-yl)phenyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate

用途与制备

ATB-343 是 Indomethacin 的衍生物，可释放 H₂S。H₂S 具有细胞保护和抗炎作用，抑制白细胞粘附于血管内皮和白细胞迁移至炎症部位。ATB-343 可用于抑制呼吸道感染。

医药

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