12192-57-3 Aurothioglucose
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安全说明
运输信息:常温运输,包装类别III,危险品运输编号2811。危险描述:皮肤致敏物1类、呼吸道致敏物1类、生殖毒性2类(20.4%)。需防护措施:P203、P233、P260、P261、P271、P272、P280、P284、P302+P352、P304+P340、P318、P321、P333+P317、P342+P316、P362+P364、P403、P405、P501。存储条件:避光,温度<40℃,优选15-30℃,避免冷冻。
用途与制备
生命科学。MEDICATION: To produce obesity in experimental animals. Parenteral: Suspension, sterile, for IM use only, 50 mg/ml; Solganal (with aluminum monosterate 2% and propylparaben 0.1% in sesame oil), Schering. 生物活性: Aurothioglucose (Gold thioglucose) is a known TrxR1 active site inhibitor, inhibits TrxR1 activity in HeLa cells without affecting cell viability. 急性毒性: 皮下-小鼠 LDL0: 1650 毫克/公斤; 静脉-鸡 LD50: 1000 毫克/公斤. 可燃性危险特性: 可燃; 燃烧产生有毒硫氧化物烟雾; 病人服用副作用为: 恶心, 呕吐, 黄疸. 储运特性: 通风低温干燥. 灭火剂: 干粉,泡沫,沙土,二氧化碳, 雾状水.
生命科学; 医药
Gold thioglucose is prepared by adding a solution of gold bromide to an aqueous solution of thioglucose that contains sulfur dioxide. After heating, the product is precipitated by the addition of ethanol.