170098-98-3 1-溴-4-氟-2-甲基-5-硝基苯

运输信息：常温运输。危险描述：非危险化学品，海关编码2904990090。未提供明确暴露限值及防护要点。

化学合成

化学合成

路线1：

• 步骤：在氩气下，将1-溴-4-氟-2-甲基苯（10mmol，1.89g）溶解在浓H₂SO₄（Sp.gr 1.18）（10mL）中，并将混合物冷却至0℃。分批加入KNO₃（10mmol，1.01g），保持温度在约0℃。然后将混合物在0℃至20℃之间搅拌2小时。将反应混合物倒入冰中，用乙醚（*2）萃取产物。将有机层合并，干燥（MgSO₄）并减压除去溶剂，得到油状产物（9.4mmol，2.2g，94％）。
• 条件：温度0-20℃，时间2小时，氩气保护
• 产率：94%
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