128577-47-9 3-氟-4-(溴甲基)苯甲酸甲酯

危险性质：非危险化学品

化学合成。

化学合成

合成路线 1（1. 合成：128577-47-9）

产率：100% 合成条件：With N-Bromosuccinimide; Perbenzoic acid In tetrachloromethane; water for 6 h; Reflux 实验步骤：溴化程序：将含有NBS（3.9g，22mmol）的CC-（40mL）中的4-甲基-3-氟 - 苯甲酸甲酯（18.3mmol）和含有25％水（0.55g，1.7mmol）的过氧化苯甲酰搅拌均匀 并加热回流6小时。 蒸发溶剂，加入K 2 CO 3水溶液，用EtOAc萃取产物，得到浅黄色固体。 4-（溴甲基）-3-氟苯甲酸甲酯产量= quant（5.9g），ESI-MS：[M + H] + = 247Da。 参考文献：

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