化学合成。
医药
合成路线 1（1. 合成：221198-99-8）
产率：93%
合成条件：With hydrogen; palladium In tetrahydrofuran at 20℃;
实验步骤：向1-（2-氟-4-硝基苯基）-4-甲基哌嗪（14.76g，61.70mmol）的THF（80mL）溶液中加入Pd / C（3.00g）。 将反应在室温下在H 2下搅拌过夜。 过滤混合物，滤液真空浓缩，得到标题化合物，为灰白色固体（11.99g，93％）。
参考文献：
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