674-26-0 甲瓦龙酸内酯

名称和标识

中文名: 甲瓦龙酸内酯
英文名: DL-Mevalonolactone
CAS号: 674-26-0
分子式: C6H10O3
分子量: 130.14
中文别名: DL-甲羟戊酸内醋; 3,5-二羟基-3-甲基戊酸内酯; DL-甲瓦龙酸内酯; 甲瓦龙酸内脂; 4-羟基-4-甲基四氢-2H-吡喃-2-酮; (±)-3-羟基-3-甲基Δ-戊内酯; (±)-Β-羟基-Β-甲基-Δ-戊内酯; (±)-甲瓦龙酸内酯
英文别名: β-Hydroxy-β-methyl-δ-valerolactone; (±)-β-Hydroxy-β-methyl-δ-valerolactone; (±)-3-Hydroxy-3-methyl δ-valerolactone; (±)-Mevalolactone; (±)-Mevalonic acid lactone; (±)-Mevalonolactone; (4S)-4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one; (S)-3,5-Dihydroxy-3-methylpentanoic acid δ-lactone; (S)-4β-Hydroxy-4-methyltetrahydro-2H-pyran-2-one; (S)-Tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one; DL-Mevalolactone; DL-Mevalonic acid lactone; (3RS)-mevalonolactone; MEVALONIC LACTONE; (+/-)-MEVALONOLACTONE; MEVALONIC ACID LACTONE,DL; (RS)-mevalonolactone; (S/R)-mevalonolactone

安全说明

WGK Germany:3 F:3-10 海关编码:29322090 存储类别:11 - 可燃固体

用途与制备

生物活性 DL-Mevalonolactone ((±) -Mevalonolactone; Mevalolactone) 是甲羟戊酸的 δ-lactone 形式，甲羟戊酸途径的一个前体。DL-Mevalonolactone (Mevalonolactone) 可以降低大脑中线粒体膜电位 (∆Ψm)，NAD (P) H 的含量和 Ca2+ 的保留能力, 而且还诱导线粒体肿胀。
靶点 Human Endogenous Metabolite

医药