27913-99-1 4-(4-甲基哌嗪)苯甲醛

危险性质：非危险化学品

化学合成。

化学合成

合成路线 1（1. 合成：27913-99-1）

产率：95% 合成条件：Stage #1: With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 0.50 h; Stage #2: at 80℃; for 6 h; 实验步骤：在4.0ml DMF中，溶解1-甲基哌嗪（0.1g，0.001mol）。 向该溶液中加入K 2 CO 3（0.20g，0.00015mol）并在搅拌下在80℃下加热。 30分钟后，加入4-氟苯甲醛（0.124克，0.001摩尔）并继续加热6小时。 反应完成后，将反应混合物冷却并逐滴加入冰水中。 将分离的产物过滤并干燥。 得到的产物是纯的，无需任何纯化即可进一步使用。（M.P.60-62°C） 参考文献：

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