作为药物中间体(具体用途未明确说明,基于其在医药相关专利中的应用)
医药
合成路线 1(1. 合成:464913-11-9)
产率:100%
合成条件:With palladium 10% on activated carbon; hydrogen In ethanol
实验步骤:步骤7 3-氨基-2-羟基-N,N-二甲基苯甲酰胺将33.5g 2-羟基-N,N-二甲基-3-硝基苯甲酰胺在600ml乙醇中的溶液加入到3.35g Pd /的悬浮液中 C在10ml的70ml乙醇中。 将反应介质在2巴氢气下搅拌过夜。 TLC和HPLC对照(t = 0.66 M + 181)。 将反应介质通过硅藻土过滤,蒸发滤液。 获得29g油状棕色固体形式的3-氨基-2-羟基-N,N-二甲基苯甲酰胺。产率=100PERCENT。
参考文献:
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