- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- CYP1A2 inhibitor
- Yes
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Fraction Csp3
- 0.3
- GI absorption
- High
- Log K p (skin permeation)
- -5.89 cm/s
- Log S (Ali)
- -3.2
- Log S (ESOL)
- -3.33
- Log S (SILICOS-IT)
- -3.84
- LogP
- 3.21
- MLOGP
- 2.64
- Molar Refractivity
- 56.88
- Num. H-bond acceptors
- 3.0
- Num. H-bond donors
- 0.0
- Num. arom. heavy atoms
- 6
- Num. heavy atoms
- 14
- Num. rotatable bonds
- 3
- P-gp substrate
- No
- PSA
- 35.53 Ų
- SILICOS-IT LogP
- 2.88
- Synthetic accessibility
- 1.77
- WLOGP
- 2.55
- XLogP3
- 2.8
- iLOGP
- 2.71
- 储存条件
- 室温，干燥密封
- 密度
- 1.4±0.1 g/cm³
- 形态
- 结晶粉末
- 折射率
- 1.535
- 水溶性
- 0.121 mg/ml ; 0.000468 mol/l
- 沸点
- 313.7±37.0 °C (760 mmHg)
- 精确质量
- 257.989136
- 蒸汽压
- 0.0±0.7 mmHg (25°C)
- 闪点
- 143.6±26.5 °C
- 颜色
- 白色
