化学合成。
医药
合成路线 1（1. 合成：97421-16-4）
产率：95%
合成条件：With palladium on activated charcoal; hydrogen In methanol at 20℃; for 3 h;
实验步骤：向25mL圆底烧瓶中加入中间体53.3（200mg，1.29mmol，1.00当量）在甲醇（4mL）和钯炭（40mg）中的溶液。 向上述混合物中引入H 2（g），并将反应在室温下搅拌3小时。 过滤固体，真空浓缩滤液，得到154mg（95％）中间体53.3，为粉红色油状物。
参考文献：
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