2-氨基-4,5-二甲氧基苯甲醛主要作为医药中间体,用于相关药物的合成研究。
医药
合成路线 1(1. 合成:22608-87-3)
产率:99%
合成条件:With 5%-palladium/activated carbon; hydrogen In tetrahydrofuran at 20℃; for 0.25 h;
实验步骤:将Pd / C(5%,0.5g)悬浮在4,5-二甲氧基-2-硝基苯甲醛(3.1,1g,4.74mmol)的无水THF(10mL)溶液中,在室温下搅拌反应混合物 在50psi压力下在氢气氛中保持15分钟。 将反应混合物通过硅藻土过滤,并将滤液减压浓缩。 通过柱色谱法纯化残余物,得到标题化合物(0.85g,99%)。
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