未明确提及具体用途,主要用于相关化学合成研究。
医药
合成路线 1(1. 合成:4969-01-1)
产率:38.8%
合成条件:at 20℃; for 4 h; Molecular sieve; Inert atmosphere
实验步骤:环己烷-1,3-二酮(500g,4459mmol),4A分子筛(500g,4459mmol)和对甲苯磺酸(254g,1338mmol)在无水乙二醇(2L)中的溶液 在室温下在氮气下搅拌4小时。 将反应混合物用饱和NaHCO 3溶液(1L)稀释以调节至碱性pH,并将碱性混合物用乙酸乙酯(3×1L)萃取。 将合并的有机萃取物用盐水溶液(500ml)洗涤,用Na 2 SO 4干燥,过滤,并在减压下浓缩,得到标题化合物(280g,1732mmol,38.8%收率),为黄色液体。 LCMS(m / z)157.1(M + H +)。
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