4-(1-1,2,4-三唑基)苯甲醛是一种用于有机合成和其他化学过程的有用的研究化学品。
有机合成
合成路线 1（1. 合成：27996-86-7）
产率：72%
合成条件：With potassium carbonate In N,N-dimethyl-formamide at 110℃;
实验步骤：通用方法：将4-氟苯乙酮/ 4-氟苯甲醛（10mmol）和咪唑/三唑（10mmol）的混合物溶于无水DMF（20mL）中。 在15分钟内将K 2 CO 3（12mmol）以小份加入上述搅拌的溶液中。 将混合物在110℃下搅拌10-12小时。 停止加热，滤出K 2 CO 3，滤液用乙酸乙酯（3×15mL）萃取。 将有机层用水（3×15mL）洗涤，用无水硫酸钠干燥并浓缩，得到油状物，将其在硅胶柱（60-120目）上纯化，用甲醇：氯仿（1:99）作为洗脱液。
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