345965-52-8 1-(4-溴苯基)环丙烷甲酸

危险性质：否

化学合成。

化学合成

路线1：以化合物XV-2为原料

• 步骤：将化合物XV-2（7.5g，33.78mmol）、KOH（7.6g，135mmol）和乙二醇（50mL）的混合物加热至160℃保持6小时；冷却至室温后加入水（200mL），用2N HCl酸化至pH=3~4，沉淀产物后过滤收集。
• 收率：69%
• 产物：化合物XV-3（5.6g），MS（ESI）m/z（M+H）+ 240
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