化学合成，Wittig烯化反应试剂。
化学合成
合成路线 1（1. 合成：1779-58-4）
产率：100%
合成条件：at 20℃; for 17 h;
实验步骤：一般步骤：向搅拌的PPh 3（1.7g，6.7mmol）的乙酸乙酯溶液中，在室温下加入2-溴乙酸甲酯（0.62μL，6.5mmol）的乙酸乙酯溶液.17小时后，得到白色沉淀物。过滤收集，用乙醚洗涤三次，在空气中干燥，得到（2-甲氧基-2-氧代乙基）三苯基溴化鏻（4,2.49g），为白色固体，几乎定量收率。将溴化鏻4（2.0g，4.81mmol）加入到乙醇钠（340mg）的乙醇（10mL）悬浮液中，然后在室温下加入3a（1.15g，4.75mmol）25分钟。在50-55℃下搅拌1小时。通过TLC监测反应进程。反应完成后，将水（10mL）加入到反应混合物中，用乙醚（20mL）萃取产物四次。合并有机层，用无水硫酸钠干燥，减压蒸发，得到固体残余物。用柱色谱（乙酸乙酯：己烷3：7）进一步纯化，得到两个肉桂酸甲酯衍生物，为E-和Z-的3.5：1混合物。同分异构体，分别为。
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