作为医药中间体或相关化合物,用于医药研发或生产过程中的关键合成步骤。
医药
合成路线 1(1. 合成:443955-90-6)
产率:61%
合成条件:With manganese(IV) oxide In dichloromethane for 72 h;
实验步骤:c)2,3-二氢 - [1,4]二恶英[2,3-c]吡啶-7-甲醛; 用二氧化锰处理(2,3-二氢 - [1,4]二氧杂环己烯[2,3-c]吡啶-7-基) - 甲醇(250mg,1.5mmol)的二氯甲烷(5mL)溶液( 650毫克,7.5毫摩尔)。 3天后,将混合物过滤并蒸发,得到白色固体(150mg,61%); MS(APCI +)m / z 166(MH +)。
参考文献:
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