61439-59-6 2-(4-苯甲氧基苯基)乙醇

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合成路线 3（3. 合成：61439-59-6）

产率：93% 合成条件：With t-butyl bromide In acetonitrile for 0.33 h; Reflux 实验步骤：通用程序：为了将PMB醚（1mmol）在乙腈（10mL）中的溶液加入，加入t-BuBr（1.1当量）并在回流下搅拌。 反应完成后（通过TLC监测），将其在减压下浓缩，将得到的粗产物溶于乙酸乙酯（50mL）中，并用饱和碳酸氢钠（25mL）洗涤。 水层用乙酸乙酯（25mL）萃取，合并的有机层用盐水溶液洗涤，干燥（MgSO 4），减压浓缩，残余物用柱色谱（硅胶，EtOAc，环己烷）纯化，得到相应的醇。。 参考文献：

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